(Adnkronos) - “L’ipoparatiroidismo comporta il non funzionamento delle ghiandole endocrine chiamate paratiroidi. Quando queste quattro piccole ghiandole, che si trovano dietro la tiroide, non funzionano, non viene secreto il paratormone (Pth)”. La diagnosi è difficile. “In un paziente con ipoparatiroidismo la sintomatologia inizialmente è di tipo neurologico e neuromuscolare. Il paziente, per questo si rivolge” in prima battuta “al neurologo, allo psichiatra per la depressione e l’ansietà”. Così Maria Luisa Brandi, medico chirurgalista in Endocrinologia e malattie intervenendo al media tutorial promosso a Milano da Ascendis Pharma.
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00:00Hypoparathyroidism is a condition, as the word says, in which endocrine glands that are called parathyroids do not work, as we talk about hypothyroidism in thyroid, for parathyroids we talk about hypoparathyroidism.
00:18We have to learn this word, which is a little difficult, and when the parathyroid glands, which are four small glands that are right behind the thyroid, for this reason they are called parathyroids, do not work, the parathyroid hormone is not secreted, which is also abbreviated with the name PTH, the patients know well this acronym PTH, and when the PTH is low or does not work on the receptor, we have a series of consequences,
00:48because the parathyroid hormone is the principal hormone that controls the calcium in the blood, it is what keeps us normal calcium, and calcium is a fundamental ion for life, because it makes the heart work, the heart cells without calcium would not contract, it makes the central nervous system work, our central nervous system needs our calcium neurons, and therefore without calcium we will not survive,
01:10and for this reason, since calcium is so scarce in the environment, we have to eat certain foods to introduce it from outside, we have supplied ourselves with a kilo of calcium element that is in our skeleton, where the parathyroid hormone removes it immediately, in order to make it available, for example, if I do not eat today, my calcium decreases, I have to take calcium and put it in the blood,
01:33so if I do not have this important function of the parathyroid hormone, which captures calcium from the bones, it captures it from the urine and brings it back to the blood, it synthesizes the dietary vitamin, so it also increases the absorption at the intestinal level, I am without calcium, and all the consequences that can be imagined, because without calcium I can also die.